Melittin: A High-Purity Peptide for Research
Melittin for Sale with Verified Purity
Melittin is a 26-residue peptide and the major constituent of honey bee venom (Apis mellifera). It has a molecular weight of 2840 Da and is cataloged under CAS number 20449-79-0. This compound exhibits strong biological activity and is widely used in scientific research across fields including microbiology, immunology, oncology, and pharmacology.
Our melittin is available in multiple sizes, including 1 mg vials, with options for bulk orders. Each batch is processed with advanced chromatography methods to purify the peptide and confirm its quality.
Key Specifications
Peptide Sequence: H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2
Molecular Weight: 2840 Da
Form: Lyophilized powder
Solubility: Compatible with aqueous buffers and organic solvents
Origin: Synthetic production for research-grade applications
Applications of Melittin in Research
Antimicrobial and Anti-Inflammatory Studies
Melittin belongs to the family of antimicrobial peptides. Research shows that melittin exhibits activity that can inhibit bacterial growth and disrupt biofilms. Studies also highlight its antiinflammatory properties, making it useful for investigating immune pathways and responses.
Cancer Research
Melittin has been studied extensively in vitro and in vivo for its effects on cancer cells. Findings indicate that melittin induces apoptosis and necrosis through disruption of the cell membrane. The mechanism of action involves pore formation and interaction with membrane lipids, leading to cytotoxicity in tumor cells including prostate cancer models and other cancer cell lines.
Immunology and Autoimmune Disease Studies
Research suggests that melittin can act as an agent influencing immune expression and antibody activity. Its ability to modulate inflammatory response pathways is of interest in studies involving autoimmune disorders.
Molecular Biology Research
Melittin binds calmodulin, activates phospholipase, and affects Ca2+ signaling, which makes it a useful tool for studying biochemical mechanisms. The peptide has been used to study the activation and inhibition of phospholipase A2, a key enzyme involved in lipid metabolism.
FAQ about Melittin for Sale
What is melattin, and is it the same as melittin?
Yes, melattin is a common misspelling of melittin. The correct name is melittin, a peptide and the main component of honey bee venom.
What are the common applications of melittin in research?
Melittin is used in studies on cancer cells, antimicrobial activity, immune response, and cell membrane interactions.
How is melittin supplied?
We provide melittin in lyophilized powder form, starting at 1 mg vials. Each order includes a safety data sheet (SDS) and technical data sheet (TDS).
Is melittin safe for personal use?
No, melittin is for laboratory research only. It is not approved for personal or medical use due to potential adverse effects such as cytotoxicity and allergic responses.